The initial maximum dosage of ferrous sulfate has been documented, alongside the formulation of astaxanthin, lycopene, ferrous gluconate, L-arginine, and multivitamin tablets that include ferrous lactate trihydrate. Additionally, enteric-coated ferrous sulfate and ferrous gluconate are associated with gastrointestinal side effects. Furthermore, the incorporation of calcium citrate XRD into these supplements can enhance their effectiveness, making it essential to consider the interactions between these components. Studies suggest that combining calcium citrate XRD with ferrous supplements could potentially minimize side effects, while maximizing absorption. Therefore, careful formulation of these supplements is crucial for achieving optimal health benefits.